Welcome to the Epidemic Preparedness Innovations (EPI) web space. This platform has been set up by the Coalition for Epidemic Preparedness Innovations (CEPI). It aims to bring together knowledge, tools and methods to support vaccine researchers, developers, funders and anybody working on or interested in the field of epidemic preparedness innovations.
Brighton Collaboration has developed more than 80 Brighton Case Definitions for adverse events following immunization (AEFI) and adverse events of special interest (AESI). The case definitions are designed to support vaccine safety studies across the entire lifespan of a vaccine. Read more
This global systematic review of both COVID-19 vaccine clinical effectiveness and neutralization capacity has directly informed and continues to inform decisions around COVID-19 vaccine policy Read more
The project is about improving capabilities of Regulators & Ethics Experts in vaccines clinical research oversight and enhancing the Maturity Level of selected ECOWAS NRAs by focused support through FDA Ghana on regulatory systems and clinical trial functions Read more
This study was designed to confirm standardised performance of SARS-CoV-2 assays used to evaluate COVID-19 vaccine candidates at the initial 7 laboratories (in North America, Europe, and Asia) of the CEPI Centralized Laboratory Network. Read more
With the support of CEPI, the Open Access version of this textbook is now available to all. It discusses how epidemiologic methods can be used to study, in real life, vaccination programmes’ impacts, benefits and risks Read more
This rapid review describes the literature for engagement and informed consent for adaptive and alternative trial designs in public health emergencies. It contrasts the approaches used for Ebola alternative design ...
SARS-CoV-2 clearance requires adaptive immunity but the contribution of neutralizing antibodies and T cells in different immune states is unclear. Here we ask which adaptive immune responses associate with clearance ...
Omicron BA.2.86 subvariant differs from Omicron BA.2 as well as recently circulating variants by over 30 mutations in the spike protein alone. Here we report on the isolation of the ...
‘12 Remarkable African Life Scientists’, by Tabitha Mwangi was published by Jacana Publishers in 2023 and is now available to download for only £1. All the money raised will ...
Evidence has shown that the risk of transmission of SARS-CoV-2 is much higher in prisons than in the community. The release of the COVID-19 vaccine and the recommendation by WHO ...
SPEAC is a project of the Coalition for Epidemic Preparedness Innovations (CEPI) and Brighton Collaboration. SPEAC provides vaccine safety tools, resources, and expertise throughout the vaccine development process to enhance safety and build confidence in vaccines.
Monitoring Vaccine Performance against SARS CoV-2 Variants
The Monitoring Vaccine Performance against SARS CoV-2 Variants Project (a global systematic review of COVID-19 vaccine clinical effectiveness and neutralization capacity) outputs are publicly available on VIEWhub to assist all policy makers
